This next-door neighbour to Cayo Coco (linked to the former by a causeway) feels more isolated and exclusive despite being only a short drive away. One of the oldest keys in development (and the tiniest) it was Hemingway who first sang the praises of Cayo Guillermo with a beautiful description in his novel Islands in the Stream. The key fiercely protects its natural environment, home to large colonies of pink flamingos!

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From £679 per person
sercotel club cayo guillermo

Sercotel Club Cayo Guillermo

3.0 stars

The perfect haven for lovers of nature in its purest state, the Villa Cojimar hotel sits in an idyllic location amidst...

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From £769 per person
iberostar daiquiri

Iberostar Daiquiri

4.0 stars

Enjoy a week of uninterrupted bliss in the Ibeorstar Daiquiri on the shores of Cayo Guillermo, a beautiful island on...

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From £829 per person
melia cayo guillermo

Melia Cayo Guillermo

5.0 stars

Stay at Melia Cayo Guillermo and make one of the most beautiful islands of Cuba's Jardines del Rey archipelago your...

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